Janet Wiles

Complex Systems from DNA to development

Multiple levels of complexity link genotypes to phenotypes, from molecules to minds. Computational modelling is a generic way of studying complexity and provides a basis for exploring the computational properties of biological systems, abstracting over the myriad details of real biology. This talk describes a multi-level approach to modelling three levels of biological complexity: nucleotide sequences, genetic networks and ontogeny (development of an organism). The talk will discuss the role that these intermediate layers play in the complexity of biological systems and the software challenges inherent in such a project.